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Benedetta publishes a review “Applications of high-throughput reporter assays to gene regulation studies” in Current Opinion in Structural Biology!

Jul 24, 2025
1 min read

Updated: Jul 27, 2025

In this review, we discuss the different ways that high-throughput reporter assays, such as MPRAs and STARR-seq, can be employed to understand transcriptional regulation by cis-regulatory elements, the effects of genetic variants on disease mechanisms, and how we can design synthetic elements with desired features. You can find the review here: https://www.sciencedirect.com/science/article/abs/pii/S0959440X2500123X?via%3Dihub


 
 
 

1 Comment


xin wang
xin wang
Oct 24

这篇综述把MPRAs和STARR-seq在顺式调控元件研究里的应用梳理得很清楚,读着挺有收获。顺便提一句,视频相关的YouTube缩略图我一般用youtube thumbnail downloader这类工具下载,像这个页面里提到的内容如果做成视频,直接通过youtube thumbnail hd方式保存会很方便。

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Juan Fuxman Bass, PhD

Associate Professor of Biology

 

Boston University

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e-mail: fuxman@bu.edu

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