What we do...​
Transcriptional regulation plays a fundamental role in development, homeostasis and the response to pathogens. Indeed, mutations in regulatory regions have been associated with multiple pathologies including autoimmune disorders, cancer, developmental malformations, and susceptibility to infections.
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Our lab aims identify the transcriptional mechanisms that control different biological processes including immune responses, cell differentiation, and viral pathogenesis. We tackle this overarching goal by integrating high-throughput screening approaches, bioinformatics analyses, and cell biology follow-up studies. Ultimately, the lessons learned from these studies will provide insights into disease mechanisms and provide a blueprint for the design of novel therapeutic approaches.
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